国际眼科纵览

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常见眼表光损害及其发病机制

张一帆宋慧赵树君南莉1   

  1. 1天津医科大学眼科临床学院 天津市眼科医院 天津市眼科学与视觉科学重点研究室 天津市眼科研究所 300002;2天津医科大学内分泌研究所 天津医科大学朱宪彝纪念医院 300134
  • 收稿日期:2019-09-21 出版日期:2020-06-22 发布日期:2020-06-22
  • 通讯作者: 南莉,Email: 13820773411@163.com
  • 基金资助:
    天津市自然科学基金(18JCDJC36400)

Common ocular surface light damage and its pathogenesis

Zhang Yifan1,  Song Hui1, Zhao Shujun2, Nan Li1   

  1. 1 Clinical College of Ophthalmology Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Lab. of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin 300002, China; 2 Tianjin Medical University Institute of Endocrinology, Zhuxianyi Memorial Hospital of Tianjin Medical University, Tianjin 300134, China
  • Received:2019-09-21 Online:2020-06-22 Published:2020-06-22
  • Contact: Nan Li, Email: 13820773411@163.com
  • Supported by:
    Natural Scientific Foundation of Tianjin (18JCDJC36400)

摘要: 眼表长期暴露于外界光线下,各种眼表光损伤疾病临床常见。以紫外线为主的短波长不可见光可以导致急性光化学角膜炎、翼状胬肉、圆锥角膜等疾病;以蓝光为代表的可见光引起的最常见眼表损伤为干眼,与电子照明和视频终端使用密切相关。光损伤引起眼表组织细胞水肿、新生血管生成以及组织增生等病理改变;主要机制与炎症、凋亡、氧化应激等相关。(国际眼科纵览, 2020, 44:196-201)

Abstract: The ocular surface is exposed to external light for a long time, and various ocular surface light damage diseases are common in the clinic. Short-wave invisible light, mainly ultraviolet rays can cause diseases such as acute photochemical keratitis, pterygium, keratoconus, etc. The most common ocular surface damage caused by visible light represented by blue light is dry eye, which is closely related to the use of electronic lighting and video terminals. Light damage causes ocular edema, angiogenesis, and tissue hyperplasia of the ocular surface. The main mechanisms are related to inflammation, apoptosis, and oxidative stress. (Int Rev Ophthalmol, 2020, 44:196-201)